Mostly everything in the area is immune to Cold and Lightning. In the Matron's Den you battle Lilith, who is Andariel's sister. Izzy drops Mephisto's Brain (that explains a lot, doesn't it?). Izzy is the easiest of the three ubers, although the Pit Lords in the area are immune to Magic, Cold, Fire, Ice, and Lighting. In the Furnace of Pain you battle Uber Izzy. These three areas all have one Uber creature, who is not immune but has extremely high resistances, a very fast health recovery rate, and all minions are 2x harder. The game randomly decides which one to open, so you may have to do this a number of times to visit all three. Transmute the three keys in Harrogath in Act 5 to open one of three portals: Furnace of Pain, Matron's Den, or the Forgotten Sands. KEY OF DESTRUCTION - Is held by Nihlathak (Halls of Pain) KEY OF HATE - Is held by The Summoner (Arcane Sanctuary)ģ. KEY OF TERROR - Is held by The Countess (The Tower)Ģ.
There are three keys, and the chance to get them is random (1 in 34 chance).ġ. This quest is only available with the v1.11 patch in Hell difficulty games on.